The emergence of synthetic cathinones, particularly MDPHP (commonly known as “monkey dust”), represents a growing public health concern. This guide will examine the drug’s history, effects, testing considerations, user demographics and firsthand experiences from users.
History of Monkey Dust
Monkey dust (MDPHP – 3′,4′-methylenedioxy-α-pyrrolidinohexiophenone) belongs to the synthetic cathinone family, commonly known as “bath salts” Synthetic cathinones are a class of lab-made stimulants chemically related to substances found in the khat plant, a shrub grown in East Africa and southern Arabia. These chemicals emerged in the early 2000s as “legal highs”¹.
First synthesized in laboratories attempting to develop new pharmaceuticals, these compounds were never approved for medical use due to their dangerous side effects and high abuse potential².
Due to the lack of medical use and high risk for abuse, synthetic cathinones like this are classified as Schedule I controlled substances.
The drug gained notoriety in the United Kingdom around 2018-2019, where a wave of highly publicized incidents led to increased public awareness and concern³. Its street name “monkey dust” reportedly comes from the bizarre and agitated behavior often exhibited by users.
How Is Monkey Dust Made?
MDPHP is structurally similar to other synthetic cathinones, particularly MDPV (methylenedioxypyrovalerone). It belongs to the pyrrolidinophenone class of stimulants⁴. The substance typically appears as:
– White or beige crystalline powder, sometimes tinted yellow or brown.
– Occasionally pressed into tablet form
– Variable purity and composition
Chemical synthesis occurs in clandestine laboratories, often with inconsistent quality control and frequent contamination with other substances⁵.
Effects on the Human Body
Monkey dust produces intense stimulant effects by affecting neurotransmitter systems⁶:
Primary Mechanisms:
– Increases dopamine release
– Blocks dopamine reuptake
– Affects norepinephrine systems
– Disrupts serotonin function
Short-term effects include:
– Intense euphoria
– Increased energy and alertness
– Elevated heart rate and blood pressure
– Hyperthermia
– Severe anxiety and paranoia
– Aggressive behavior
– Hallucinations
– Delusional thinking
Long-term effects may include:
– Cardiovascular damage
– Cognitive impairment
– Persistent psychosis
– Kidney dysfunction/failure
– Severe dental problems
– Addiction and dependence
The rush begins within 30-90 minutes, with peak effects lasting about 3 hours. Increased energy, focus and alertness is typical from around hour 2 to 6. At about hour 6, the “comedown” effects will begin, marked by anxiety, intense paranoia and psychosis.
Drug Testing Methods
Currently, DOT and most non-DOT jobs do not routinely test for Monkey Dust or other synthetic cathinones. However, if there is high suspicion of use, there are drug testing methods that can determine if somebody has recently used the substance.
Available Testing Methods:
– Gas chromatography-mass spectrometry (GC-MS)
– Liquid chromatography-mass spectrometry (LC-MS)
– Immunoassay: Randox Drugs of Abuse V Biochip Array Technology (DOA-V)
– Point of Care: the UK is selling rapid test kits which give results in 3-5 minutes. The test cutoff for positive results is 500 ng/mL or above.
How Long Can Monkey Dust Be Detected?
– Blood: 24-48 hours
– Urine: 2-4 days
– Hair: Up to 90 days
Many standard drug tests do not detect synthetic cathinones without specific modification, making monitoring and detection difficult7.
Accessibility and Distribution
The distribution patterns of monkey dust reflect broader trends in synthetic drug trafficking8:
Primary Sources:
– Clandestine laboratories in Asia; primarily in China, India and Pakistan
– Dark web marketplaces: used to connect producers to distribution networks overseas
– Local synthesis operations
– Cross-border trafficking networks
Distribution Methods:
– Online sales
– Street-level dealing
– Mail delivery systems
– Social media platforms
Cost and Market Dynamics
The pricing structure varies significantly by region and availability9:
According to law enforcement reports, here are some typical price points for Monkey Dust on the street:
– Individual doses: $5-15
– Pressed tablets: $10-20 each
– Bulk powder: $20-40 per gram
Factors affecting price:
– Geographic location
– Supply chain disruptions
– Law enforcement activity
– Market competition
– Purity levels
Who Is Using Monkey Dust?
Research indicates specific patterns among monkey dust users10:
Primary User Groups:
– Males aged 18-35
– Previous stimulant users
– Nightlife scene participants
– Individuals with history of substance abuse
Geographic Distribution:
– Urban centers
– Areas with established stimulant markets
– Regions with limited treatment resources
– Communities with high unemployment
Risk factors associated with use:
– Prior substance use disorder
– Mental health conditions
– Limited access to healthcare
– Low income
What Are People Saying About Monkey Dust?
According to feedback from Monkey Dust users in the Reddit community, commonly occurring themes include:
Frightening hallucinations like being attacked by large insects and being surrounded by “shadow people”.
Multiple days with no sleep and no appetite, with 3-5 days at a time not being uncommon. They mention a strong urge to keep redosing in order to avoid the impending comedown effects.
A deep psychosis and remaining in an extended zombie-like state.
Many users got a horrible sense of paranoia.
Some say the rush in the beginning was too weak and not as strong as other cathinones like Mephedrone or Hexen.
There were a small handful of users that experienced positive effects. They said that they felt more creative, had intense laser-like focus, and high energy levels.
To sum it up, there were a few users who did enjoy it, though the majority did not have a pleasant experience. Most users said they were not impressed and that they would most likely not try it again.
Conclusion
Monkey dust represents a significant public health challenge that requires a coordinated response from healthcare providers, law enforcement, and the community. The substance’s unpredictable effects, difficult detection, and evolving distribution patterns necessitate continued research and adaptive intervention strategies.
For anyone struggling with substance use, professional help is available through:
– National Drug Helpline
– Local addiction treatment centers
– Emergency medical services
– Mental health crisis lines
References
1. European Monitoring Centre for Drugs and Drug Addiction. “Synthetic Cathinones Drug Profile.” 2023
2. Journal of Analytical Toxicology. “Analysis of Novel Psychoactive Substances.” 2023
3. UK Home Office. “Drug Misuse Report.” 2023
4. Chemistry Research & Toxicology. “Structural Analysis of Synthetic Cathinones.” 2023
5. Drug Testing and Analysis. “Detection Methods for Novel Psychoactive Substances.” 2024
6. Neuropharmacology Journal. “Mechanisms of Synthetic Cathinone Action.” 2023
7. Clinical Chemistry. “Detection Windows for Novel Psychoactive Substances.” 2024
8. United Nations Office on Drugs and Crime. “World Drug Report.” 2023
9. Drug Enforcement Administration. “Drug Threat Assessment.” 2023
10. Addiction Research & Theory. “Demographics of Synthetic Stimulant Use.” 2024